Posts Tagged ‘infertility’

It’s easy to describe pregnancy: it occurs when a sperm fertilizes an egg. But the process that brings it about is not so simple. For a man to get his partner pregnant:

  • He must produce a large number of healthy sperm and deliver them close to the woman’s cervix.
  • The sperm must be active enough to reach the egg and then strong enough to penetrate the egg.

Infertility can result if there’s a hitch in sperm quality, production or delivery. People often assume that infertility is solely a woman’s problem. But male factors account for about 40 percent of infertility cases. Luckily, treatment can help a couple overcome male-factor infertility.

Treatments for male infertility

The right treatment will depend on what is causing infertility. Often surgery or medication may be tried first.

    • Varicocele (a varicose vein in the scrotum)
    • Blockage in the ducts that carry sperm
    • Structural defect present since birth or caused by infection or surgery
  • Surgery can be done to fix common problems such as a:

Surgery can often be done using tiny incisions that cause only minimal pain and scarring.

  • Medications may be used to treat some men. For example, hormones can be used to correct a low testosterone level. And antibiotics may help if infertility is caused by an infection.

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Press Release:

Literature Review Finds No Indication that Soy Decreases Testosterone Levels

ST LOUIS, July 20 /PRNewswire/ — A new study published by the American Society for Reproductive Medicine finds that soyfoods and soy isoflavone supplements have no significant effect on male reproductive hormone levels in men. The literature review indicates that soy does not decrease testosterone levels.

Led by Jill M. Hamilton-Reeves, PhD, RD, of St. Catherine’s University, St. Paul, Minnesota, researchers assessed the effects of soy protein and soy isoflavones on measurements of male reproductive hormones. Findings, just published online in Fertility and Sterility, a publication of the American Society for Reproductive Medicine, demonstrate no significant effect of soy protein or soy isoflavone intake on circulating levels of testosterone, sex hormone-binding globulin or free testosterone in men.

The comprehensive meta-analysis examined the existing scientific literature including all clinical studies examining soy’s effect on male reproductive hormones published before July 1, 2008. Fifteen placebo-controlled treatment groups with baseline and ending measures were analyzed. Thirty-two reports involving 36 treatment groups were also assessed in simpler statistical models. Studies published after July 1, 2008, which were not included in the meta-analysis, support the conclusions of the meta-analysis.

Reproductive endocrinologist William R. Phipps, MD, of the University of Rochester Medical Center, a co-author of the analysis stated, “As a high-quality source of protein that is relatively low in saturated fat, soy can be an important part of a heart-healthy diet and may contribute to a decreased risk of coronary heart disease.” He noted that some men have been reluctant to consume soyfoods due to concerns about estrogen-like effects of soy isoflavones, often referred to as phytoestrogens. But according to Phipps, “it is important for the public to understand that there is no clinical evidence to support these ideas. After conducting a comprehensive review of the existing literature, we found no indication that soy significantly alters male sex hormone levels.”

Men can benefit from soyfood consumption as a means to meet daily protein requirements and at the same time possibly also reducing their risk of heart disease.

Citing the research study, Lisa Kelly, MPH, RD, of the United Soybean Board, added, “Soy is often praised for the positive role it can play in the diets of women. But, years of clinical research have shown that men stand to benefit from soy, too. I encourage men to incorporate soyfoods into a balanced and varied diet and talk to their healthcare provider about their own unique nutritional needs.”

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LOS ANGELES—Blue Cross of California complied with state law when it offered only $2,000 in annual coverage for fertility treatments and was not obligated to cover the entire cost, a California appellate court ruled. At issue in Wednesday’s ruling by the state appellate court in Los Angeles was a renewal package offered by Thousand Oaks, Calif.-based Blue Cross of California to Santa Barbara, Calif.-based Westmont College. The offer included paying a maximum of $2,000 a year for half of the cost of treating a group member for infertility, which complied with a state mandate that obligates insurers to offer infertility coverage, according to the ruling in Deborah Dunn Yeager vs. Blue Cross of California.

Westmont refused to buy the coverage, in part because of its high cost. Ms. Yeager, a Westmont employee, was unable to become pregnant without medical assistance and could afford only limited infertility treatment, which proved ineffective, according to the decision.

She sued Blue Cross in 2006, alleging unfair competition and false advertising. Ms. Yeager sought recovery for her out-of-pocket expenses for the infertility treatment above Blue Cross’s $2,000 annual limit and “for her pain and suffering from losing her chance to bear a child.”

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Biostar Pharmaceuticals, Inc. (BSPM.OB) received local approval for three TCM products, which it expects to begin selling later this month. The company projects a total of $3.5 million in revenues from the three products in 2009, and $7.4 million in 2010. Biostar anticipates they will produce net income of $1 million this year and $2 million in 2010.

Biostar has built a rural cooperative medicine supply network to distribute these products alongside its existing drugs. The network currently consists of about 1,320 sales outlets in rural areas, which Biostar plans to expand into 10,000 sales outlets in two years.

The three new products are:

  • Yizi Capsules – a TCM aimed at infertility in women and believed to aid in healthy fetal development during pregnancy. It is one of only a few nutritional supplement products marketed for infertility

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Seems like a terrible and heartless thing to ever say, right? The death of the oldest woman to give birth from in vitro fertilization (IVF) was announced this week; she was 69 years old and is survived by her twin sons. This naturally brings up a lot of questions I hear from women on a regular basis concerning IVF and assisted reproduction technologies (ART).

Women are waiting longer on average to begin having children in the last 20-30 years due to careers, education and other opportunities not traditionally available to women. As a result, more women are finding that natural conception has become increasingly difficult. On the opposite side of this coin is the “Octomom” fiasco in which a woman with no medical need for IVF was given a rather radical treatment resulting in the birth of 8 children.

Why the difficulty?

It is common knowledge that women over the age of 30 begin to experience marked declines in potential fertility. The primary reason for this decrease in fertility is the age of the eggs which her body is supporting to maturation.

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UPDATE: There were some questions as to the science that was presented. Research had been released by California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment. The scientists presented their evidence before the “science advisory board’s developmental and reproductive toxicant identification committee,” which composed of eight doctors from various fields of medicine. The doctors heard testimony from almost 30 people, including myself — an environmental advocate — and members of the canned goods industry. -Elisa

OAKLAND, Calif. — Despite day-long presentations of scientific data and heartfelt testimony by breast cancer survivors and concerned mothers, a panel of eight doctors unanimously voted against listing the chemical bisphenol A as a neurological and reproductive toxin under the state’s Proposition 65.

Proposition 65, which was passed by voters in 1986 to protect people from chemicals known to cause cancer, birth defects and reproductive harm, requires the governor to publish at least annually a list of these toxic chemicals.

At least a dozen studies have suggested bisphenol A, or BPAs that are found in numerous plastic products, including baby bottles, sippy cups and the inside linings of cans, can cause infertility problems like low sperm count and miscarriage and increase a woman’s risk of breast cancer. But the doctors sided with the industry, saying the animal sample sizes of these studies were too small and that the doses of BPAs were inconsistent to demonstrate a clear link between the chemical and these dire illnesses.

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Researchers at the Northeast England Stem Cell Institute have come up with a way to create human sperm from embryonic stem cells. The journal Stem Cells and Development last week published research led by Karim Nayernia, of Newcastle University.

The research isn’t intended to make men obsolete. On the contrary, the science behind it could someday give couples struggling with fertility hope for starting a family.

What Nayernia and his team of scientists did was come up with a way to turn embryonic stem cells with male chromosomes into reproductive cells.

They then divided the cells, which in turn produced sperm.

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Press Release:

Fertility Centers of Illinois Becomes the First IVF Center in Illinois to Offer Advanced Embryo Selection Techniques, Testing All 24 Chromosomes

CHICAGO–(BUSINESS WIRE)–Fertility Centers of Illinois (FCI) is one of the first centers in the U.S., to offer a new and more advanced method of Preimplantation Genetic Diagnosis (PGD), a technique that can detect and eliminate abnormalities and genetic disorders in children such as Down Syndrome, Turners Syndrome, Kleinfelters Syndrome and more. The new technology called Microarray, is far more thorough and accurate than previous methods of testing.

Used in conjunction with In Vitro Fertilization (IVF), PGD is a cutting-edge technique that screens embryos for chromosomal abnormalities and genetic disorders prior to implantation. Such genetic conditions can interfere with Embryo Implantation, result in pregnancy loss, or the birth of a child with physical problems, developmental delay or mental retardation.

This new technology screens all 24 chromosomes and provides rapid results, eliminating the need to freeze embryos which can sometimes harm viability. Previous methods of PGD could only test a maximum of 9 – 12 chromosomes, leaving 12 or more untested. This caused 1 in 4 cases of aneuploidy – a chromosome abnormality - to be missed and if transferred, embryos that were unlikely to create healthy pregnancies.

Dr. Angeline Beltsos, reproductive endocrinologist with Fertility Centers of Illinois explains that this new PGD technology will provide better information to help select the best embryos for transfer during IVF. “The ability to test all 24 chromosomes and more accurately identify abnormal embryos may drastically improve pregnancy outcomes for ‘at risk’ couples, as well as significantly increase their odds of a healthy pregnancy and baby,” she adds.

Candidates for PGD testing include those experiencing recurrent miscarriage, previous unsuccessful IVF cycles, unexplained infertility, male factor infertility, or women of advanced maternal age.

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Springfield, MO) — Traffic, work, family, these are all things that can give us stress on a daily basis. But you might not know that stress can also make it harder for you to get pregnant.

A new study from the University of California, Berkley found that when we experience high levels of stress, our bodies create a type of hormone that suppresses our ability to reproduce. Locally, doctor’s say that’s something they’ve always suspected, but now they have proof.

Amy is an attorney with a successful career, a stable marriage and a nine year old daughter. A year and a half ago she & her husband decided to try for another, but they were having trouble. “It’s really strange because anything I wanted in my life I’ve been able to do,” said Amy.

Amy didn’t want to show her face for this interview because she’s uncomfortable in front of the camera. And she thinks there’s a stigma attached to words like infertility. “It’s quite devastating because you walk around in the grocery story and you see the mom’s and the babies and then your friends have baby showers and its like, well why can’t I do this,” said Amy.

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Like many other women, Cheryl Hall was afflicted with infertility. After taking one leave from work, and requesting a second, to undergo in vitro fertilization (IVF), she was fired. Does Title VII, the main federal anti-discrimination law, prohibit an employer from firing an employee under these circumstances? In a recent ruling, Hall v. Nalco, the U.S. Court of Appeals for the Seventh Circuit said yes.

Conflicts between Reproduction (Including Infertility Treatment) and Work

There is no inherent conflict between reproduction and work. But certainly pregnant women sometimes face challenges at work, whether posed by environmental conditions, like chemicals, radiation, or infectious disease; or by physical movements that can be difficult to perform, like standing for long periods of time, stooping over, climbing stairs or ladders, or lifting heavy objects; or, finally, by job conditions, like irregular hours, shift work, or psychological stress. As I have written in previous columns such as this one, the law protects against pregnancy “discrimination,” but provides little in the way of forcing employers to accommodate the women’s condition, and ameliorate the conflict between being pregnant and fulfilling certain job conditions, in these situations.

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