Posts Tagged ‘research’

Researchers at the Northeast England Stem Cell Institute have come up with a way to create human sperm from embryonic stem cells. The journal Stem Cells and Development last week published research led by Karim Nayernia, of Newcastle University.

The research isn’t intended to make men obsolete. On the contrary, the science behind it could someday give couples struggling with fertility hope for starting a family.

What Nayernia and his team of scientists did was come up with a way to turn embryonic stem cells with male chromosomes into reproductive cells.

They then divided the cells, which in turn produced sperm.

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Yale researchers may have solved a fundamental medical mystery: how bisphenol A (BPA), a ubiquitous plastics component, changes genetic chemistry and impairs fertility.

The Yale team’s findings, previewed earlier this month to the Endocrine Society, a 14,000-member scientific and medical professional organization devoted to hormone system research and treatment, have intensified scientists’ concern that exposure BPA, a synthetic estrogen that disrupts the endocrine system, may have grave consequences for human reproduction.

In an interview, study co-author Hugh S. Taylor, M.D., professor and chief of the reproductive endocrinology section at Yale University School of Medicine, said his team injected pregnant mice with BPA for just one week. After those mice, and a control group, gave birth, the scientists found that the genetic chemistry of female offspring exposed to BPA in the womb had been irrevocably altered.

A particular gene known as HOXA10, responsible for normal uterine development and fertility in both mice and humans, had been stripped of numerous so-called “methyl groups,” each composed of a single hydrogen atom and three carbon atoms.

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by Abasalt Hosseinzadeh Colagar, MD, et al.

BERKELEY, CA (UroToday.com) - Insufficient intake of zinc (Zn) can impair antioxidant defenses and may be an important risk factor in oxidant release, compromising the mechanism of DNA repair, and making the sperm cell highly susceptible to oxidative damage. In the absence of Zn, the possibility of increased oxidative damage exists that would contribute to poor sperm quality. Infertile men and men who smoke are very susceptible to oxidative damage induced by free radicals. In the present study, we hypothesized that major changes in the level of seminal Zn levels are related with low quality of sperm and poor fertilizing capacity.

Semen samples were collected from fertile (smoker [n = 17], nonsmoker [n = 19]) and infertile men (smoker [n = 15], nonsmoker [n = 21]). After collection, semen specimens were allowed to liquefy at room temperature for 30 minutes and used for parameters analysis. On microscopic examination, sperm count, percentage of motile sperm, and sperm with normal morphology were objectively evaluated. Semen samples were centrifuged at 600g for 10 minutes. After centrifugation, supernatants were diluted 10-fold by deionized water. Levels of Zn were measured by atomic absorption spectroscopy (AAS).

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Washington, June 16: Researchers from University of California, Berkeley claim to have found a missing piece of puzzle about how stress causes sexual dysfunction and infertility.

The study showed that stress delivers a double whammy on reproductive system and fertility.

It is already known that stress boosts levels of stress hormones - glucocorticoids such as cortisol - that inhibit the body’s main sex hormone, gonadotropin releasing hormone (GnRH), and subsequently suppresses sperm count, ovulation and sexual activity.

However, the new study showed that stress also increases brain levels of a reproductive hormone named gonadotropin-inhibitory hormone, or GnIH, discovered nine years ago in birds and known to be present in humans and other mammals.

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ScienceDaily (June 15, 2009) — It was long believed that conception does not involve a meeting of equals. The egg is a relatively large, impressive biological factory compared with the tiny sperm, which delivers to the egg one copy of the father’s genes. However, a new study from Huntsman Cancer Institute (HCI) at the University of Utah reveals that the father’s sperm delivers much more complex genetic material than previously thought. The findings could lead to a diagnostic test to help couples deal with infertility.

Researchers discovered particular genes packaged in a special way within the sperm, and that may promote the development of the fetus.

“Our findings show that the father plays an active role in packaging his genome to help ensure a healthy baby,” says study co-leader Brad Cairns, Ph.D., investigator with HCI and the Howard Hughes Medical Institute, and professor of oncological sciences at the University of Utah. “However, they also raise the possibility that a man’s aging, health and lifestyle may alter this packaging and negatively affect fertility and embryo development.”

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Press Release:

WASHINGTON, June 11 /PRNewswire-USNewswire/ – June is Men’s Health Month, a perfect time to summarize the science showing that soyfoods — from tofu, soymilk, edamame, soy yogurt and frozen dairy-free soy treats to non-meat alternatives, soy nuts, soy nut butter, and/or cereals and bars with soy — promote the health of men by helping to protect against prostate cancer, reduce the risk of cardiovascular disease and aide in weight management.

“Today more than ever before, the science is clear: a large body of research documents important health benefits for men who consume soyfoods and does not conclusively find any negative effects on male fertility or erectile function,” said Nancy Chapman, RD, MPH, Executive Director of the Soyfoods Association of North America.

The weight of scientific evidence examining how soy affects men’s health continues to show soy intake has no effect on erectile function, testosterone levels, reproductive hormones, sperm motility, or sperm quality. This evidence includes a large body of U.S. government and National Institute of Health-sponsored human and primate research, in which controlled amounts of isoflavones from soy were fed and no effect on quantity, quality or motility of sperm were observed. In fact, a small-scale, preliminary study by Dr. Jorge Chavarro (1) found that “soyfood and soy isoflavone intakes were unrelated to total sperm count, ejaculate volume, sperm motility, or sperm morphology,” which are the important measures of sperm quality and male infertility.

Misperceptions have developed regarding the estrogen-mimicking phytoestrogens and several men’s health problems, including erectile dysfunction (ED). According to the American Urological Association Foundation, there is no association between soyfoods and ED. Rather, the causes of this condition include damage to nerves, muscle, or tissue; lifestyle choices including smoking and being overweight; psychological factors such as stress or depression; and several common medicines used to treat high blood pressure and depression. Additionally, there are no clinical research studies linking soyfoods with a lack of men’s sexual performance, low sperm count or infertility.

A study of prostate mortality rates in 42 countries documented significantly lower prostate cancer death rates with soy consumption.(2) A growing body of research suggests that regular consumption of soyfoods may reduce the risk of prostate cancer by as much as 30 percent. (3, 4)

At a time when heart disease remains the leading cause of death for men, (5) a growing body of research continues to find that soy protein lowers both the total amount of cholesterol and the so-called “bad” low-density lipoprotein (LDL) cholesterol. In addition, soy protein may also help maintain or moderately increase the “good” high-density lipoprotein (HDL) cholesterol, (6) and may help lower triglycerides, which both are linked with improved heart health. These findings reinforce the science behind the health claim approved by the Food and Drug Administration in 1999 stating “25 grams of soy protein a day, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease.” While the health claim is currently under review to assess the effect of more recent data, a substantial amount of research conducted since the original soy protein health claim continues to support the role of soy protein as part of a heart healthy diet. (7, 8, 9)

For the estimated 68.3 million men over the age of 20 who are classified as overweight or obese,(10) an evidence-based review conducted by the University of Illinois at Champagne-Urbana finds soy protein is equal to other protein sources, such as dairy or meat, in helping to battle weight by promoting fat loss. (11) Findings from this review also support the possibility that soy protein helps decrease short-term appetite and calorie intake, which is why men battling extra pounds should try soyfoods to curb cravings and replace foods high in calories, saturated fat and cholesterol.

Men can have complete confidence that eating soyfoods is not only safe, but also that soy is a healthy option. For the most part, soyfoods are easily digestible, low in calories and saturated fat, and contain no cholesterol. Improved men’s health and eating soyfoods go hand-in-hand. For more information, please visit www.soyfoods.org.

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By Christopher J. Petherick The head of the German agriculture department has issued new guidelines that effectively ban a type of genetically modified corn, which has been made in a laboratory by scientists at biotech giant Monsanto.

The variety of corn, called “MON 810” and sold under its trade name “Yield Guard,” has been altered on a genetic level, making it resistant to the corn borer, a moth larva that consumes the plant and kills it.

MON 810 is grown extensively around the world. According to Agbios, an online database on genetically modified crops, more than 32 million acres in the United States has been planted with this type of GM corn.

Germany is following in the footsteps of several other EU countries—Austria, Hungary, Greece, France and Luxembourg—which have already banned it in spite of threats of sanctions from globalist groups.

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LIVINGSTON, N.J., June 3, 2009 /PRNewswire via COMTEX/ —-A group of fertility experts, who pioneered the development of Preimplantation Genetic Screening (PGS), are sharing the step-by-step best practices and explaining what errors can be made along the way.

The article, published in the latest edition of Fertility and Sterility, details when PGS should be used, emphasizes proper embryo biopsy technique and reveals the most common errors made with the ultimate goal of educating clinics, embryologists and other experts to improve pregnancy outcomes.

When done correctly, PGS can be used to improve the success of in vitro fertilization (IVF) for women of advanced maternal age and recurrent pregnancy loss. Research shows that many times IVF fails because a majority of embryos created in vitro are chromosomally abnormal. When done correctly, PGS screens the most important chromosomes in terms of preimplantation aneuploidy (22, 16, 21 and 15), improving implantation rates.

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Press Release:

Sippy Downs, Qld, June 04, 2009 — The number of couples who want to choose the gender of their unborn baby is ever increasing. According to a recent study in USA a third of couples would look to determine baby gender. There are a number of methods available - these range from very costly treatments to pregnancy old wives tales.

The costly include IVF method, PGD and ericcson method. PGD can cost upto $20,000 and is very invasive. As with all IVF the chances of getting pregnant are not 100% but if you do get pregnant the desired gender is guaranteed 100%. This method also carries the risk of multiple pregnancies.

Ericsson method filters the male sperm from the female sperm. The sperm of the desired gender is inseminated. To conceive a boy the success rate is 70-75% and to conceive a girl 70-72%.

There is also the Shettles method for predicting baby gender which is mainly down to timing. This proves difficult for women unable to pinpoint ovulation and can take months of charting etc.

Some other methods to predict baby gender include looking at whether there is a full moon, diet and even sexual positions!

There is however another method that is not costly or invasive and is also backed by a 100% money back guarantee:
http://www.thebabypredictor.com/

visit below for baby gender quiz and more information on choosing baby gender and the baby gender test:
http://determiningbabygender.blogspot.com/ or squidoo lense for more on baby gender and answers to baby gender
quiz: http://www.squidoo.com/babygenderpredictors

contact
Hayley Hewitt
Blossom
22 James Cook Drive
Sippy Downs, Qld 4556
Australia
0407-171-805
hayley-buster@bigpond.com
http://www.thebabypredictor.com

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A group of leading doctors has warned the public to avoid genetically modified food and GMOs (Genetically Modified Organisms). A revealing press release from this group of concerned physicians states, “The American Academy of Environmental Medicine (AAEM) today released its position paper on Genetically Modified foods stating that ‘GM foods pose a serious health risk’ and calling for a moratorium on GM foods.”

The critical information here is largely taken with permission from an excellent article written by respected health researcher Jeffrey Smith on this key topic so vital to our health.

On May 19th, the AAEM posted their landmark paper calling on “Physicians to educate their patients, the medical community, and the public to avoid GM (genetically modified) foods when possible and provide educational materials concerning GM foods and health risks. In addition to a moratorium on GM foods, these doctors also called for non-biased, long-term independent studies, and labeling of all foods containing GM ingredients.

AAEM’s position paper stated, “Several animal studies indicate serious health risks associated with GM food,” including infertility, immune problems, accelerated aging, insulin regulation, and changes in major organs and the gastrointestinal system. They conclude, “There is more than a casual association between GM foods and adverse health effects. There is causation,” as defined by recognized scientific criteria. “The strength of association and consistency between GM foods and disease is confirmed in several animal studies.”

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